William E Fahl Selected Research

3- (methylamino)- 2- ((methylamino)methyl)propane- 1- thiol

1/2022	Significant Reduction of Total-Body Irradiation-Induced Death in Mice Treated with PrC-210 24 Hours Postirradiation.
1/2021	Determination of plasma levels of the active thiol form of the direct-acting PrC-210 ROS-scavenger using a fluorescence-based assay.
1/2021	Suppression of Inflammation-Associated Kidney Damage Post-Transplant Using the New PrC-210 Free Radical Scavenger in Rats.
8/2020	Significant Improvement in Rat Kidney Cold Storage Using UW Organ Preservation Solution Supplemented With the Immediate-Acting PrC-210 Free Radical Scavenger.
1/2020	Impact of the PrC-210 Radioprotector Molecule on Cancer Deaths in p53-Deficient Mice.
7/2019	Significant Reduction of Murine Renal Ischemia-Reperfusion Cell Death Using the Immediate-Acting PrC-210 Reactive Oxygen Species Scavenger.
1/2019	Significant reduction of ischemia-reperfusion cell death in mouse myocardial infarcts using the immediate-acting PrC-210 ROS-scavenger.
7/2013	Radioprotective efficacy and toxicity of a new family of aminothiol analogs.
7/2012	ROS-scavenger and radioprotective efficacy of the new PrC-210 aminothiol.
4/2012	A new orally active, aminothiol radioprotector-free of nausea and hypotension side effects at its highest radioprotective doses.

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William E Fahl Research Topics

Disease

6	Neoplasms (Cancer) 01/2020 - 08/2014
4	Body Weight (Weight, Body) 01/2022 - 04/2012
4	Vomiting 01/2021 - 04/2012
4	Nausea 01/2021 - 04/2012
4	Hypotension (Low Blood Pressure) 01/2021 - 04/2012
4	Stomatitis 12/2018 - 04/2014
4	Dermatitis 12/2017 - 07/2013
3	Ischemia 01/2021 - 01/2019
3	Radiodermatitis 12/2017 - 07/2012
2	Myocardial Infarction 01/2021 - 01/2019
2	Reperfusion Injury 08/2020 - 01/2019
2	Leukemia 01/2020 - 06/2016
2	Alopecia (Baldness) 06/2016 - 01/2015
2	Weight Loss (Weight Reduction) 02/2015 - 04/2014
1	Acute Radiation Syndrome 01/2022
1	Inflammation (Inflammations) 01/2021
1	Necrosis 08/2020
1	Carcinogenesis 01/2020
1	Lymphoma (Lymphomas) 01/2020
1	Radiation-Induced Neoplasms (Neoplasms, Radiation Induced) 01/2020
1	Pain (Aches) 12/2018
1	Breast Neoplasms (Breast Cancer) 12/2017
1	Leukemia L1210 06/2016
1	Hypoxia (Hypoxemia) 01/2015
1	Syncope (Fainting) 04/2012

Drug/Important Bio-Agent (IBA)

10	3- (methylamino)- 2- ((methylamino)methyl)propane- 1- thiolIBA 01/2022 - 04/2012
8	Vasoconstrictor AgentsIBA 12/2018 - 04/2014
5	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 12/2016 - 04/2014
5	Norepinephrine (Noradrenaline)FDA LinkGeneric 12/2016 - 08/2014
4	Amifostine (Ethyol)FDA LinkGeneric 01/2021 - 04/2012
4	Adrenergic Agents (Adrenergic Drugs)IBA 12/2018 - 02/2015
4	Epinephrine (Adrenaline)FDA LinkGeneric 12/2016 - 01/2015
2	AntioxidantsIBA 08/2020 - 01/2019
2	DNA (Deoxyribonucleic Acid)IBA 08/2020 - 01/2020
2	Sulfhydryl Compounds (Thiols)IBA 01/2020 - 07/2013
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2018 - 06/2016
2	Adrenergic Receptors (Adrenergic Receptor)IBA 12/2016 - 08/2014
2	Pharmaceutical PreparationsIBA 01/2015 - 04/2012
1	Free Radical ScavengersIBA 01/2021
1	CytokinesIBA 01/2021
1	CaspasesIBA 08/2020
1	University of Wisconsin-lactobionate solutionIBA 08/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2019
1	N-(2-mercaptoethyl)-1,3-diaminopropaneIBA 01/2019
1	Narcotics (Narcotic Analgesics)IBA 12/2018
1	Adrenergic Agonists (Adrenergic Receptor Agonist)IBA 12/2016
1	CarbonIBA 07/2013
1	SolutionsIBA 07/2012
1	Ethanol (Ethyl Alcohol)IBA 07/2012
1	Propylene Glycol (1,2 Propanediol)FDA LinkGeneric 07/2012

Therapy/Procedure

6	Radiotherapy 12/2017 - 04/2014
3	Drug Therapy (Chemotherapy) 06/2016 - 04/2014
2	Transplantation 01/2021 - 07/2019
2	Therapeutics 06/2016 - 01/2015
1	Segmental Mastectomy (Lumpectomy) 12/2017
1	Intravenous Injections 06/2016
1	Drug Tapering 07/2012
1	Controlled Hypotension 04/2012